Caplyta's Side Effects, Utilization in Bipolar Disorder, Pricing, and Dosage Details Provided

Caplyta's Side Effects, Utilization in Bipolar Disorder, Pricing, and Dosage Details Provided

Caplyta is a branded pill used for dealing with schizophrenia and bipolar disorder. The primary active substance in Caplyta is lumateperone, categorizing it under the atypical antipsychotics drug class.

The Food and Drug Administration (FDA) has authorized Caplyta to manage the following issues in adults:

• schizophrenia
• depressive phases stemming from bipolar I or bipolar II disorder

Doctors may prescribe Caplyta independently or in combination with either lithium (Lithobid) or valproate for treating depressive phases.

Drug specifics

Below, you can find significant information about Caplyta:

• Drug category: atypical antipsychotics, or second-generation antipsychotics
• Medication form: pill
• Availability in generic form: no
• Requires prescription: yes
• Classified as a controlled substance: no
• Year of FDA approval: 2019

Caplyta generic form

At present, Caplyta is only available as a branded medication. It does not have a generic counterpart.

A generic medicine is an identical version of the active drug in branded medication. Generics typically cost less than branded drugs.

Caplyta side effects

Caplyta can lead to mild or severe side effects. The following tables contain some of the main side effects that might occur while using Caplyta. These lists do not include all possible side effects.

For more information about the potential side effects of Caplyta, see this article. You can also discuss any concerns with your doctor or pharmacist. They can provide you with tips on how to manage any side effects.

Note: The Food and Drug Administration (FDA) tracks side effects associated with drugs it has authorized. If you have experienced a side effect while using Caplyta, you can report it through MedWatch.

Mild side effects

Mild side effects of Caplyta are outlined in the table below. This table indicates which condition individuals were taking Caplyta for when the side effect occurred in clinical trials.

Note: This is a summary of mild side effects from Caplyta. To learn about other mild side effects, consult your doctor or pharmacist, or check Caplyta's prescribing information.

| In people taking Caplyta for schizophrenia | In people taking Caplyta for bipolar disorder ||---|---|| drowsiness | Yes | Yes || dry mouth | Yes | Yes || nausea or vomiting | Yes | Yes || lightheadedness | Yes | Yes || lack of appetite | Yes || tiredness | Yes || weight gain | Yes | Yes || increased liver enzymes (which may indicate liver damage) | Yes || increased levels of creatine phosphokinase* (which might indicate damage to muscle, brain, or heart tissue) | Yes || headache | Yes || diarrhea | Yes || stomach pain | Yes || respiratory infection, such as a common cold | Yes || blurry vision | Yes || elevated blood levels of prolactin (a hormone with various functions in the body) | Yes |

Most of these side effects should decrease or be manageable. But if they get worse or persist, talk with your doctor or pharmacist.

For more information about this side effect, see “Side effect details” below.

Serious side effects

sleepiness*

While serious side effects from Caplyta are rare, they can occur. Contact your doctor immediately if you have serious side effects. Contact 911 or your local emergency number if your symptoms feel life-threatening or if you believe you're having a medical emergency.

Serious side effects and their symptoms can include:

• Neuroleptic Malignant Syndrome (a rare yet severe reaction to using antipsychotic medications). Signs might include:
  • sweating profusely
  • a blistering high fever (around 106.7°F/42°C)
  • muscle rigidity or stiffness (difficulty relaxing muscles as usual)
  • cognitive impairment or mental confusion (sudden and severe confusion)
  • loss of consciousness (stupor)
  • unstable blood pressure
• Orthostatic Hypotension (a decrease in blood pressure when standing up). Symptoms can include:
  • dizziness
  • fainting
  • falling down
• Decreased number of white blood cells, such as neutrophils (white blood cells that fight infections). Symptoms may encompass:
  • high temperature
  • exhaustion or fatigue
  • persistent infections
• High sugar levels in the blood or diabetes. Symptoms can include:
  • blurred vision
  • sudden weight loss
  • urinating more frequently than usual
  • weakness or fatigue
  • fruit-scented breath
• Excessive levels of blood fats, for instance, low-density lipoprotein (LDL) or total cholesterol, or triglycerides. This usually shows no symptoms and is usually identified via a blood test.
• Difficulty swallowing.* Symptoms can manifest as:
  • choking or gagging on food
  • inhaling saliva, food, or other matter into your lungs (aspiration)
  • constant coughing or hoarseness
• Difficulty regulating body temperature.* Symptoms can include:
  • lack of perspiration, even in hot weather
  • feeling overheated
  • warm skin
• Seizures.* Symptoms can include:
  • shaking uncontrollably
  • loss of consciousness
  • falling down
• Higher death risk in older adults with dementia-related psychosis.†‡
• Higher risk of suicidal thoughts or actions.†‡
• Abnormal muscle movements or body convulsions, including tardive dyskinesia.‡
• Allergic reaction.‡

* This side effect was not reported in the clinical trials for Caplyta. However, this has occurred with other antipsychotic medications. It may also occur with Caplyta.† Caplyta has a boxed warning for this side effect. A boxed warning is the most serious warning from the FDA.‡ For more information about this side effect, see “Side effect details” below.

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Help is within reach

If you or another person is in crisis and contemplating suicide or self-harm, please seek assistance:

• Contact or message the 988 Lifeline at 988 or visit 988lifeline.org. Caring specialists are available for support 24/7 at no charge and confidentially.
• Send HOME to the Crisis Text Line at 741741 to connect with a volunteer crisis specialist for 24/7, no-cost support.
• Not in the United States? Locate a helpline in your country using Befrienders Worldwide.
• Dial 911 or your local emergency services number if you feel secure doing so.

If you're calling on behalf of someone else, stay with them until they receive assistance. Remove any harmful objects if you can do so safely.

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If you're not residing in the same building, keep them on the phone until assistance arrives.

Side effect specifics

Check out details on certain potential side effects this medication might provoke.

Increased risk of death in certain elderly individuals

Elderly individuals with psychosis linked to dementia may have an increased risk of death when receiving antipsychotic medications, such as Caplyta. In fact, this drug has a boxed warning for this risk. A boxed warning alerts physicians and patients about drug effects that may be harmful.

Psychosis refers to a mental health condition where individuals lose touch with reality. Dementia is a group of symptoms affecting memory, thinking, speaking skills, and behavior that negatively impact daily living.

In addition, elderly individuals with dementia-related psychosis may have an increased risk of stroke when receiving antipsychotic medications, such as Caplyta.

The clinical trials for Caplyta had only a few participants aged 65 years and older. Studies of other atypical antipsychotic drugs have reported strokes and, in some cases, death in elderly individuals with dementia-related psychosis. (Caplyta is an atypical antipsychotic.)

dry mouth

Causes of death have been:

• heart failure
• sudden death
• pneumonia (a severe lung infection)
• stroke

Caplyta is exclusively intended for adults and has not been examined in children. The effectiveness of medications used for treating depression has been shown to heighten the risk of suicidal thoughts and actions in children and adults aged 24 years or younger. This risk applies to Caplyta due to its purpose of treating depressive episodes stemming from bipolar I or bipolar II disorder.

Suicidal thoughts and actions could be more prevalent during the initial stages of Caplyta therapy and after adjustments in dosage. It's also possible for these thoughts and actions to be indicators of underlying mental health issues, including those treated by Caplyta.

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You and your healthcare provider will collaborate to monitor any alterations in your behavior while using Caplyta. Your doctor might suggest that individuals close to you, such as friends or family members, observe any shifts in your behavior during Caplyta treatment as well.

Should your condition worsen or you experience newly escalating or persisting suicidal thoughts or actions, promptly communicate with your doctor. They may recommend adjustments in your Caplyta dosage or discontinuation of the treatment.

Drowsiness

Caplyta may induce drowsiness. In clinical trials for the drug, drowsiness was the most frequently reported side effect.

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This side effect is often mild and might subside after a few weeks or months. However, it can impair your ability to think clearly or execute motor skills (muscle movements or actions). Therefore, you should refrain from driving or operating machinery until you have a clear understanding of how Caplyta affects you.

Persistent drowsiness with this drug should be discussed with your doctor. They may recommend taking your Caplyta dose before bedtime to minimize daytime drowsiness.

Before commencing Caplyta treatment, consult with your doctor, as well as your caregiver, loved ones, or friends. They may be able to assist you with tasks that you may be too tired to perform, such as shopping, preparing meals, and completing household chores.

Atypical muscle or body movements

Using Caplyta may lead to atypical muscle or body movements, also referred to as extrapyramidal effects. Symptoms can include:

• muscle spasms, stiffness, or rigidity
• floppy muscles
• involuntary jerks, tremors, or twitches
• drooling
• sticking out your tongue or smacking your lips
• difficulty swallowing
• repetitive or uncontrollable body movements
• inability to move muscles

One type of extrapyramidal effect is a movement disorder called dystonia. The prevalence of dystonia symptoms, such as muscle spasms, twitches, and stiffness, with Caplyta is not explicitly determined. They usually appear more frequently with older antipsychotic drugs. (Caplyta is a newer drug categorized as an atypical antipsychotic.)

Dystonia symptoms may occur more frequently in males or younger individuals. The frequency of dystonia occurrence with Caplyta can be found in its prescribing information.

nausea or vomiting

Another type of extrapyramidal effect is tardive dyskinesia. It can be severe and typically involves involuntary facial movements that you cannot control. Tardive dyskinesia may subside once you discontinue Caplyta, reoccur, or persist indefinitely.

If you experience any of the aforementioned symptoms during Caplyta treatment, inform your doctor immediately. They may recommend lowering your dose or suggest an alternative medication.

* Sex and gender exist on spectra. The term “male” in this article refers to sex assigned at birth.

Allergic reaction

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As with most drugs, some individuals may develop an allergic reaction after taking Caplyta.

In uncommon instances, Caplyta has prompted symptoms of a mild allergic reaction, including:

• rash
• itchiness
• hives

Flushing can also be a sign of mild allergic reactions.

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Although less frequent, a more severe allergic reaction is also possible. Symptoms of a severe allergic reaction can include:

• swelling under the skin, commonly in the eyelids, lips, hands, or feet
• swelling of the tongue, mouth, or throat
• difficulty breathing

If you have an allergic reaction to Caplyta, promptly contact your doctor. In the event that your symptoms become severe, call 911 or your local emergency number if you suspect a medical emergency.

In the event of an allergic reaction to Caplyta, your doctor will typically recommend an alternative medication.

The signs of schizophrenia can vary, but you might feel like your sense of reality is skewed. This is known as delusional perception. You could experience delusional symptoms such as seeing or hearing things that aren't real (known as hallucinations) or holding unfounded beliefs or thoughts (called delusions). Other symptoms may include:

• experiencing depression
• feeling distant, unmotivated, or devoid of feelings
• finding it difficult to concentrate or focus
• feeling less joy in life or relationships
• having trouble making decisions or solving problems

Treatment for schizophrenia

Treatment for schizophrenia involves two main components:

dizziness

• Controlling symptoms: Antipsychotic medications, like Caplyta, are primarily used to manage symptoms of schizophrenia. Caplyta is a type of antipsychotic drug.
• Support for daily living: Your doctor might suggest therapy, support groups, or education for family and caregivers, as well as other specialized programs. These can help you and others with relationships, daily tasks, and activities.

To learn more about caring for your mental well-being, check out our mental health section.

Effectiveness of Caplyta for schizophrenia

In two research studies, Caplyta was shown to be effective in managing symptoms of schizophrenia.

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The American Psychiatric Association also recommends that schizophrenia patients be treated with antipsychotic drugs, such as Caplyta.

Caplyta and children

Caplyta is not approved to treat schizophrenia in children. It's not known whether the drug is safe or effective for children.

Caplyta for bipolar disorder

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The U.S. Food and Drug Administration (FDA) approves certain prescription drugs, like Caplyta, for specific conditions. Caplyta might also be used off-label for other conditions. Off-label drug use refers to utilizing a drug for a purpose that it hasn't been authorized for by the FDA.

Caplyta is FDA-approved to treat depressive episodes caused by bipolar I or bipolar II disorder in adults. This use is discussed below. Caplyta is also FDA-approved to treat schizophrenia, details of which can be found in the "Caplyta for schizophrenia" section.

About bipolar disorder

Bipolar I disorder and bipolar II disorder are mental health conditions characterized by episodes of manic behavior or hypomanic episodes (milder manic episodes) and episodes of depression. Manic or hypomanic episodes might involve increased energy or an exaggerated sense of self-confidence. Depressive episodes, often referred to as bipolar depression, can cause sadness, loneliness, or a lack of interest in activities once enjoyed.

Caplyta is used to treat depressive episodes associated with bipolar I and bipolar II in adults. Your doctor may prescribe the drug alone or in combination with lithium (Lithobid) or valproate. These are other medicines that could help with bipolar disorder.

Treatment for bipolar disorder

Treatment for bipolar disorder can consist of:

• Symptom management: Antipsychotic drugs, antidepressants, and other medications may be prescribed to manage symptoms of bipolar disorder. Caplyta is an antipsychotic drug.
• Support for daily living: Therapy, support groups, and education for family and caregivers, as well as other specialized programs, may be recommended to help with relationships, daily tasks, and activities.

lack of appetite

Visit our mental health section for more information on caring for your mental health.

Caplyta's effectiveness for bipolar disorder

In two research studies, Caplyta was shown to be effective in treating depressive episodes in individuals with bipolar I or bipolar II.

For details about the drug's performance in clinical trials, see Caplyta's prescribing information.

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Caplyta and children

Caplyta is not authorized to treat depressive episodes related to bipolar disorder in children. It's not known whether the drug is safe or effective for use in children.

Caplyta cost and discounts

Medication prices can vary, and the actual cost you'll pay may depend on your insurance plan, location, and pharmacy. You may be able to get a 90-day supply of Caplyta, which could reduce your number of pharmacy visits and lower the overall cost. If eligible, discuss this option with your doctor or insurance company.

Your insurance company may require pre-authorization for Caplyta. This involves communication between your doctor and the insurance company regarding your prescription before coverage is granted. The insurance company will review the pre-authorization request and determine if the drug will be covered.

If you're unsure whether pre-authorization is required for Caplyta, contact your insurance company.

For more information about Caplyta and its cost, see this article.

Caplyta coupons

fatigue

Explore the discount coupons below to help save on your Caplyta prescription.

You can also visit this site for Caplyta's price estimates using these discount coupons.

Note: Caplyta discount coupons cannot be used with insurance co-pays or benefits.

* Optum Perks is a sister site of Medical News Today.

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Financial and Insurance Assistance

If you're struggling to cover Caplyta costs or need help understanding your insurance coverage, aid is out there.

A savings card and additional resources are on hand for Caplyta. For further details and to check your eligibility for financial aid, go to the manufacturer's website.

Mail-Order Pharmacies

Caplyta might be available via mail-order pharmacies. This service could lower drug costs and enable you to get your medication without leaving home.

If recommended by your doctor, you might be eligible for a 90-day supply of Caplyta, reducing worries about running out. For this option, consult your doctor and insurance provider. Certain Medicare plans may help cover mail-order medication expenses.

If you lack insurance, ask your doctor or pharmacist about online pharmacy choices.

Generic Version

weight gain

Currently, Caplyta isn't available in a generic form. A generic medication is a direct replica of a drug's active ingredient in a brand-name medicine. Generics tend to be more affordable than brand-name drugs.

How Caplyta functions

Caplyta is utilized to treat schizophrenia and depressive episodes stemming from bipolar I and bipolar II disorder in adults.

Schizophrenia is a mental health issue that can impact feelings, perceptions, thoughts, and behavior. Bipolar disorder is also a mental health disorder, inducing episodes of mania or hypomania and episodes of depression.

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The precise causes of schizophrenia and depressive episodes in bipolar disorder aren't identified. However, medical experts think that symptoms of these conditions are, in part, caused by the imbalanced activity of neurotransmitters (brain chemicals). Examples of neurotransmitters include dopamine and serotonin. They influence mood, thinking, perceptions, and behaviors.

How Caplyta works to treat schizophrenia and bipolar disorder

A drug's mode of action is known as its mechanism of action. The mechanism of action of Caplyta in treating schizophrenia and depressive episodes associated with bipolar disorder is not clear.

However, Caplyta is a kind of medication called an antipsychotic. Medications in this category are believed to function by altering the activity of dopamine and serotonin in the brain.

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When these brain chemicals and their receptors are impacted, symptoms of schizophrenia and depressive episodes in bipolar disorder may be decreased. (Receptors are proteins in the brain that neurotransmitters must attach to in order to produce their effects.)

How long does it take to work?

After beginning Caplyta treatment, it might take around a week for Caplyta to take effect. And it may take another few weeks or more for you to detect a change in your symptoms.

In two clinical trials, people's symptoms of schizophrenia significantly eased after taking Caplyta for 4 weeks. In two additional clinical trials, people's depressive symptoms caused by bipolar disorder eased within 6 weeks of initiating the drug.

If you're using Caplyta for schizophrenia and have concerns about its effectiveness, discuss this with your doctor.

Caplyta dosage

The following information covers the Caplyta dosage often used or suggested. However, your doctor will determine the best dosage for you. Always take the precise Caplyta dosage your doctor prescribes for you.

Detailed information about Caplyta's dosage can be found in this article.

increased levels of liver enzymes (which may be a sign of liver damage)

Drug forms and strengths

Caplyta comes in capsule form, which you swallow. It's available in three strengths: 10.5 milligrams (mg), 21 mg, and 42 mg.

Dosage for schizophrenia

Caplyta is approved to treat schizophrenia in adults. The standard dosage for this condition is 42 mg once daily.

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Your doctor may prescribe a lower dosage of Caplyta if you have liver problems or if you're taking certain medications.

You can take Caplyta with or without food. However, you should not take the drug with grapefruit or grapefruit juice.

See the “Caplyta interactions” section below for details about potential Caplyta interactions and examples of drugs that might interfere with Caplyta.

Dosage for bipolar disorder

Caplyta is approved to treat depressive episodes due to bipolar I and bipolar II in adults. The standard dosage for this condition is 42 mg once daily.

Your doctor may prescribe a lower dosage of Caplyta if you have liver problems or if you're taking certain medications.

You can take Caplyta with or without food. However, you should not take the drug with grapefruit or grapefruit juice.

See the “Caplyta interactions” section below for details about potential Caplyta interactions and examples of drugs that might interfere with Caplyta.

increased levels of creatine phosphokinase (which may indicate damage to muscle, brain, or heart tissue)

What if I miss a dose?

Try to take your Caplyta dose at the same time each day. If you forget a dose, take it as soon as you remember. But if it's almost time for your next dose, skip the missed dose and return to your usual schedule. Do not double up or take more Caplyta to make up for missed doses.

To help ensure that you don't miss a dose, use a medication alarm. This could include setting an alarm or timer on your phone or downloading a reminder app. A kitchen timer can also work.

Long-term mental health conditions such as schizophrenia and bipolar disorder often require prolonged treatment, and antipsychotic medications, like Caplyta, are commonly suggested by doctors. If Caplyta is deemed safe and effective for you, it becomes a long-term component of your mental health management plan.

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Frequently Asked Questions about Caplyta

Here are answers to frequently asked concerns regarding Caplyta.

Operating machinery or driving while on Caplyta

It's advised against operating any machinery or driving until you're familiar with Caplyta's effects on you. This is due to drowsiness being a common side effect of the drug. In fact, drowsiness was the most common side effect in clinical trials of Caplyta.

Drowsiness can:

• impact your thought clarity
• reduce your ability to focus
• affect your motor skills
• slow your reaction time

Sometimes, drowsiness may fade away, or you might be able to manage it. For instance, your doctor may advise you to take Caplyta before bedtime to help reduce daytime drowsiness.

If you're anxious about drowsiness while utilizing Caplyta, consult your doctor. You can also refer to "Drowsiness" in the "Caplyta side effects" section above.

headache

Tests required while using Caplyta

Your doctor will frequently order some lab tests before and throughout your Caplyta treatment. These tests are conducted to monitor potential serious adverse effects of the medicine.

The following are typical lab tests for Caplyta:

• Blood sugar: Antipsychotic drugs like Caplyta can cause high blood sugar levels. If left untreated, this can lead to severe or life-threatening conditions such as diabetic ketoacidosis (harmful levels of ketones in the blood). To check for this side effect, your doctor will test your blood sugar levels before and during Caplyta treatment.
• Cholesterol and triglycerides: Antipsychotics can influence your cholesterol and triglyceride levels. Changes in these blood fats can increase the risk of heart or blood vessel disease. To monitor this side effect, your doctor will test your blood cholesterol and triglyceride levels before and during Caplyta treatment.
• White blood cell counts: Although unlikely, Caplyta may cause low white blood cell levels, including neutrophils (white blood cells that fight infection). Other antipsychotics have caused a severe, life-threatening low white blood cell level called agranulocytosis. If you had or have a low white blood cell count, your doctor will monitor your levels frequently during the initial months of Caplyta treatment. If your levels decrease, they might recommend discontinuing the medication.

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If you have additional questions about the required lab tests for your Caplyta treatment, consult your doctor.

Caplyta and alcohol

Alcohol doesn't interact with Caplyta. However, alcohol consumption while on Caplyta may intensify some side effects, such as nausea, vomiting, dizziness, sleepiness, and fatigue.

Additionally, it's possible that alcohol usage while dealing with mental health conditions, such as schizophrenia or bipolar disorder, may lead to alcohol dependence. With dependence, your body needs the substance to function normally. Alcohol use disorder is more common among individuals with mental health conditions than among those without them.

If you consume alcohol and are considering taking Caplyta, discuss this with your doctor.

Caplyta interactions

Caplyta can interact with numerous medications and certain supplements as well as certain foods.

Various interactions may result in different effects. For example, some interactions can hinder a drug's efficacy. Other interactions can raise the number of side effects or make them more severe.

diarrhea

To learn more about Caplyta's interactions, see this article.

Caplyta and other medications

Below is a list of medications that can interact with Caplyta. This list does not include all drugs that may interact with Caplyta.

Before taking Caplyta, communicate openly with your doctor and pharmacist. Share all your prescription, over-the-counter, and other medications, as well as any vitamins, herbs, and supplements that you use. Being transparent can help you avoid potential interactions.

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If you have questions about drug interactions that may apply to you, consult your doctor or pharmacist.

Administering Caplyta along with certain medications may affect how your body metabolizes or processes Caplyta. The level of Caplyta may become excessively high, increasing the risk of side effects.

Examples of medications that may boost the level of Caplyta in your body include:

• ciprofloxacin (Cipro)
• diltiazem (Cardizem CD, Cartia XT, Tiazac)
• fluconazole (Diflucan)
• clarithromycin
• ritonavir (Norvir)
• valproic acid

Other medications might diminish the effectiveness of Caplyta in treating your condition, as they could reduce its levels in your body. Some medications that might have this impact include:

• carbamazepine (Tegretol)
• phenytoin (Dilantin)
• prednisone (Rayos)
• rifampin (Rifadin)
• efavirenz

Your doctor will inform you whether Caplyta is compatible with these medications or if a dosage adjustment is necessary if you're currently taking Caplyta.

Caplyta and herbs and supplements

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During Caplyta treatment, it's advisable not to ingest any products containing the herb St. John's wort. Exposure to this herb can cause your liver to metabolize excessive amounts of Caplyta, resulting in diminished effectiveness.

Many individuals use St. John's wort and other herbs for mental health improvement. Nonetheless, it's essential to confirm their safety and efficacy with your physician or pharmacist beforehand.

Caplyta and foods

Throughout your Caplyta therapy, avoid consuming grapefruit or drinking grapefruit juice.

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Grapefruit consumption or drinking grapefruit juice may impede your liver's capability to break down Caplyta. This may result in the concentration of Caplyta in your system becoming excessively high and leading to side effects. (For further information on side effects, refer to the "Caplyta side effects" section above.)

If you have any inquiries regarding grapefruit and Caplyta, consult your physician or pharmacist.

How to take Caplyta

Follow the instructions provided by your doctor or healthcare expert for administering Caplyta.

Caplyta is available in capsule form, which you should swallow whole.

When to take

Typically, you'll take Caplyta once daily. You can take it at any time, but it's recommended to maintain a consistent schedule, taking it around the same time each day.

Should you feel excessively drowsy after taking Caplyta, discuss this with your doctor. They may recommend taking your dose before bedtime to minimize daytime drowsiness.

upper respiratory infection, such as the common cold

To prevent skipping doses, you may follow medication reminder strategies such as setting reminders on your phone or utilizing a reminder app. A kitchen timer can also be effective.

Taking Caplyta with food

You can administer Caplyta with or without food. Nonetheless, you should avoid consuming grapefruit or grapefruit juice during your Caplyta therapy. Doing so might heighten the risk of side effects. For more specifics, refer to "Caplyta and foods" in the "Caplyta interactions" section above.

Can Caplyta be crushed, opened, or chewed?

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It's crucial not to crush, open, or chew Caplyta capsules. To function effectively, you should swallow the capsules whole.

If you encounter difficulties when swallowing Caplyta capsules, consult your doctor or pharmacist promptly. It's essential to adhere to your treatment plan and avoid missing any doses.

Caplyta and pregnancy, breastfeeding, and birth control

If you have the potential to become pregnant, are breastfeeding, or are using birth control, consider whether Caplyta is a suitable option for you.

For additional information, consult this article. If you have further inquiries, discuss them with your doctor.

Caplyta precautions

Caplyta carries several precautions.

FDA warnings

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This drug carries the following FDA warnings regarding significant risks:

Increased mortality risk in older adults with dementia-related psychosis: Older adults with psychosis related to dementia may have an elevated mortality risk upon treatment with antipsychotic drugs. Therefore, Caplyta is not authorized for use in older adults with such conditions.

Psychosis refers to a mental health disorder in which individuals lose their grasp of reality. Dementia encompasses a collection of impairing symptoms associated with memory, thinking, speech, and behavioral changes.

Increased risk of suicidal thoughts and behaviors in children and young adults: Individuals under 24 years may have an increased risk of suicidal thoughts and behaviors arising or worsening when undergoing drugs used for depression treatment. Caplyta is prescribed for treating depressive episodes caused by bipolar I or bipolar II disorder.

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On account of this risk, Caplyta is not prescribed for children. You and your doctor will collaborate to monitor you for any behavioral changes while using Caplyta.

For comprehensive details, refer to "Side effect details" in the "Caplyta side effects" section above.

Low white blood cell count: Caplyta might decrease your white blood cell count, including neutrophil count. If you have previously had issues with low white blood cell count, inform your doctor about it. For further details, check out "Do I need to undergo regular lab tests while using Caplyta?" under the "Frequently Asked Questions about Caplyta" section above.

Low blood pressure syndrome: Caplyta may enhance the risk of orthostatic hypotension. Individuals with low blood pressure or who are on blood pressure medication are more susceptible. Consult your doctor before starting Caplyta. If you suffer from low blood pressure, your doctor may monitor your condition more frequently during your treatment.

Cardiovascular health issues: Caplyta might increase the risk of orthostatic hypotension. Those with cardiovascular disease are more vulnerable. Discuss Caplyta with your doctor before use. Regular monitoring might be necessary during your treatment if you have cardiovascular issues.

Seizure or epilepsy history: Caplyta may enhance the chance of seizures. People with a history of seizures or epilepsy are at higher risk. Share any such history with your healthcare provider. They can help determine whether Caplyta is suitable for you.

Dehydration or heatstroke risk: Caplyta may make it harder for your body to regulate its temperature. This could lead to overheating, which can be dangerous. Caplyta may also cause orthostatic hypotension. Individuals with a higher risk of these side effects include those who are often dehydrated or prone to overheating.

Stay hydrated when using Caplyta. Avoid intense exercises, saunas, and hot environments until you understand how Caplyta affects you. Talk to your doctor about the potential risks of heat-related issues before starting treatment.

increased blood levels of prolactin (a hormone with various functions in the body)

Liver disease: If you have liver disease, speak with your doctor before starting Caplyta. Mild liver disease should not typically affect your dosage, but moderate or severe liver disease may require a lower dosage than usual.

Diabetes complications: Caplyta can cause high blood sugar levels, which may worsen diabetes in affected individuals. Inform your doctor about your diabetes before beginning Caplyta. They may advise you to monitor your blood sugar levels more frequently.

High cholesterol or triglyceride levels: Caplyta may elevate the levels of cholesterol or triglycerides in your blood. Inform your doctor if you already have high cholesterol or triglyceride levels before starting Caplyta. Regular monitoring of these levels may be necessary during Caplyta treatment.

Allergic reaction: If you have experienced an allergic reaction to Caplyta or any of its components, do not take Caplyta. Consult your doctor about alternative medication options.

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Pregnancy concerns: The safety of Caplyta during pregnancy is unknown. For further information about Caplyta, pregnancy, breastfeeding, and birth control, refer to this article.

Breastfeeding concerns: The safety of Caplyta during breastfeeding is uncertain. For more information about Caplyta, pregnancy, breastfeeding, and birth control, see this article.

Note: To learn more about the potential negative effects of Caplyta, check out the "Side Effects of Caplyta" section above.

Caplyta overdose

Do not exceed the recommended dosage set by your doctor. Exceeding the dosage may cause unwanted side effects or overdose.

What to do if you overdose on Caplyta

If you believe you have taken too much of this medication, contact your doctor immediately. Besides, you can also reach out to America's Poison Centers at 800-222-1222 or use their online tool. However, if your symptoms are severe, call 911 or visit the nearest emergency room immediately.

Caplyta expiration, storage, and disposal

Upon receiving Caplyta from the pharmacy, the pharmacist will put an expiration date on the medication label. This date is usually 1 year from the date of dispensing the medication.

The expiration date ensures that the medication remains effective during this period. The Food and Drug Administration (FDA) recommends avoiding expired medications. If you have unused medication that has surpassed its expiration date, discuss disposal options with your pharmacist.

Storage

The efficacy of a medication can be affected by various factors, including storage conditions.

Store Caplyta capsules at room temperature, preferably in the original blister packaging. Alternatively, you can put them in a tight, child-resistant medication container. Do not store Caplyta in bathrooms, where it may get damp or wet.

Disposal

Proper disposal of unused or expired medication is crucial to prevent accidental usage by children or pets and to minimize environmental impact.

This article offers helpful tips on medication disposal. You can also ask your pharmacist about safe disposal methods for your medication.

Alert: Medical Newscast has gone to great lengths to ensure that all the info is medically accurate, thorough, and current. However, this article should not be utilized as a replacement for the expertise and knowledge of a licensed medical professional. It's essential to consult with your doctor or other healthcare expert before starting any medication. The pharmaceutical details contained within this content are subject to change and are not designed to cover all potential uses, directions, cautions, warnings, drug interactions, allergic reactions, or negative side effects. The omission of warnings or additional information for a particular drug does not imply that the drug or drug combination is safe, effective, or suitable for all patients or all specific uses.

1. It's important to note that Caplyta, despite not having a generic form, can interact with other medications such as lithium (Lithobid) or valproate to manage depressive phases in adults with bipolar disorder.
2. Caplyta, an atypical antipsychotic, has been associated with mild side effects such as drowsiness, dry mouth, nausea, or vomiting, while severe side effects like Neuroleptic Malignant Syndrome are rare but require immediate medical attention.

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