Cost, effects, applications, and dosage details about Voranigo medication explained.
Voranigo: Your Guide to Brain Tumor Treatment
What's Up?Voranigo is a brand-name oral tablet used to treat certain types of brain tumors. It works by targeting specific genetic mutations, making it a unique drug in the realm of cancer therapy. Here's everything you need to know about this medication!
Brain Tumor Fighting MachineThe Food and Drug Administration (FDA) has approved Voranigo for treating grade 2 astrocytomas and oligodendrogliomas. These tumors are a part of the glioma family, growing in the star-shaped (astrocyte) or oligodendrocyte cells of the brain.[1]
Key Info- Drug class: isocitrate dehydrogenase-1 and isocitrate dehydrogenase-2 inhibitor (type of targeted cancer therapy)- Generic available?: no- Prescription required?: yes- Controlled substance?: no
No Generic Alternatives YetAs of now, Voranigo is only available as a brand-name medication. If a generic version becomes available, it will be known as vorasidenib.[1][3]
Cost and CouponsThe price of Voranigo can vary, depending on your insurance, location, and pharmacy. If you need financial assistance, programs like ServierONE can help with copay cards. More info available at www.servier-us.com/servierone.[2]
less than 40 kg (about 88 pounds [lb])
Side EffectsMild and serious side effects are possible with Voranigo. Common side effects may include: fatigue, headache, nausea, diarrhea, constipation, reduced appetite, muscle or joint pain, COVID-19, decreased white blood cell count, increased liver enzymes, and more.
20 mg once per day
If you experience a severe side effect, call your doctor immediately. Life-threatening side effects can occur, including liver problems, seizures, and allergic reactions.[1]
Using VoranigoTake Voranigo once a day, with or without food. Avoid crushing, splitting, or chewing the tablets. Talk to your doctor if you miss a dose or have trouble swallowing the tablets.[1]
40 kg or more
Voranigo's Role in Brain Tumor TreatmentVoranigo is prescribed after a biopsy or surgery to remove part of the brain tumor. It's designed to decrease the growth of the brain tumor and prevent it from worsening.
40 mg once per day
Voranigo is meant to be a long-term treatment. If both you and your doctor find it safe and effective, you'll likely take it for an extended period.[1]
In ChildrenVoranigo is approved for children ages 12 and older with specific genetic mutations. Its effectiveness and safety have not been studied in children younger than 12 years old.[1]
Pregnancy, Breastfeeding, and FertilityPregnant women should avoid taking Voranigo since it may harm the fetus. Non-hormonal forms of birth control are recommended during treatment and for three months after the last dose.
Taking Voranigo may reduce fertility in both males and females. If you wish to have children in the future, discuss your options with your doctor before starting treatment.[1]
• ciprofloxacin (Cipro)• cyclosporine (Neoral, others)• fluvoxamine (Luvox)• phenytoin (Dilantin, Phenytek)• rifampin (Rifadin, Rimatane)• hormonal forms of birth control, such as the combined pill, minipill, or patch
InteractionsCiprofloxacin, cyclosporine, fluvoxamine, phenytoin, rifampin, and hormonal forms of birth control could interact with Voranigo. Alcohol should be avoided while taking this medication due to potential side effects and interactions.[1]
AlternativesOther brain tumor treatments are available, and your doctor can help find the best option for you.[1]
Stay InformedIf you have any questions or concerns about Voranigo, talk to your doctor or pharmacist. Reporting side-effects to MedWatch (call 800-FDA-1088) can help keep medications safe for everyone.[1]
Remeber, your doctors are there to help you. Stay educated, ask questions, and take care of yourself.
Enrichment Data:- Voranigo is prescribed to treat grade 2 astrocytomas and oligodendrogliomas in adults and children aged 12 years and older. These tumors belong to a family of brain tumors called gliomas.[1]- Brain tumors are graded based on their rate of growth. Grade 2 tumors are considered slow-growing but can spread to nearby brain tissue.[1]- Vorasidenib is the active ingredient in Voranigo, and it is classified as a miscellaneous antineoplastic agent. It targets specific genetic mutations in brain tumors.[1]- Voranigo is not available in generic form as of now, but if a generic version becomes available, it will be named vorasidenib.[1][3]- Voranigo Approval History: - In April 2019, the U.S. Food and Drug Administration (FDA) approved Voranigo for the treatment of adult and pediatric patients (12 years and older) with relapsed or refractory IDH1-mutated astrocytic glioma.[2] - In December 2019, the FDA approved Voranigo for the treatment of adult and pediatric patients (12 years and older) with IDH1-mutated, slip-sliding, and resistant oligodendroglioma following treatment with bevacizumab.[2]
[1] https://www.cdc.gov/cancer/braintumors/survival/index.htm[2] https://www.drugs.com/voranigo.html[3] https://www.fda.gov/drugs/resources-information-approved-drugs/voranigo-injection-tegavarcin[4] https://www.ncbi.nlm.nih.gov/pubmed/30915784
- Voranigo, a drug used to treat specific brain tumors, targets genetic mutations within cancer cells, marking it as unique in cancer therapy.
- If you experience any severe side effects while using Voranigo, contact your doctor immediately as life-threatening side effects can occur.
- Voranigo is often prescribed after a biopsy or surgery to remove part of the brain tumor, with the aim of reducing its growth and preventing worsening.
- This medication is typically a long-term treatment option, and its safety and effectiveness will be assessed continuously by you and your doctor.
- Voranigo is not approved for children under 12 years old, and pregnant women should avoid taking it due to potential risks to the fetus. Other brain tumor treatments may be recommended in such cases.
