Cost, effects, applications, dosage, and additional details about Voranigo pharmaceutical product
Rebranded and Refreshed
Hey there! So, you're looking to learn more about Voranigo, huh? Voranigo is a brand-name pill that's prescribed for certain types of brain tumors. The active ingredient it contains is vorasidenib.
The FDA has given the green light to Voranigo to treat grade 2 astrocytomas and oligodendrogliomas in adults and kids aged 12 or older. You'll find these tumors under the umbrella of a group called gliomas. Astrocytomas start in brain cells called astrocytes, while oligodendrogliomas start in brain cells called oligodendrocytes.
Drug Scoop
- drug class: isocitrate dehydrogenase-1 and isocitrate dehydrogenase-2 inhibitor (a type of targeted cancer therapy)
- generic available? no
- prescription required? yes
- controlled substance? no
Voranigo Generic
At the moment, Voranigo is exclusivity available in its brand-name form. Meanwhile, a generic version of the drug hasn't been developed yet.
Generics, when available, are typically cheaper since they're exact copies of the active ingredient in a brand-name medication.
Cost and Coupons
As with any medicine, the price of Voranigo can vary depending on factors like insurance coverage, location, and the region of the pharmacy you choose.
If you need financial support, programs like ServierONE are at your service. They offer help with insurance and copay costs for Voranigo. You can reach them at 800-813-5905 or through their website for more information.
Side Effects
Voranigo can trigger mild or severe side effects. Here are some potential consequences:
- Fatigue
- Headache
- Nausea
- Diarrhea
- Constipation
- Appetite loss
- Muscle or joint pain
- COVID-19
- Lowered white blood cell count
- Increased liver enzymes
Most mild side effects will pass within a few days to a few weeks, but if they worsen, don't hesitate to contact your doctor or pharmacist.
For information about serious side effects, see the next section.
less than 40 kg (about 88 pounds [lb])
Serious Side Effects
Serious side effects are less common, but they can occur. Call your doctor right away if you encounter:
- Liver problems: Like pain in your upper right abdomen, loss of appetite, feeling lethargic or weak, dark urine, or jaundice.
- Seizures: Symptoms like staring into space, rapid blinking, or jerking body movements may indicate seizures.
20 mg once per day
ALLERGIC REACTION
An allergic reaction is possible but wasn't reported in the drug's studies. If you suspect an allergic reaction, look out for symptoms such as hives or difficulty breathing, and reach out to your doctor or pharmacist right away.
Voranigo Uses
For Certain Brain Tumors
Voranigo is approved to treat certain brain tumors in adults and kids aged 12 or older, specifically grade 2 astrocytomas and oligodendrogliomas that have an IDH1 or IDH2 mutation.
Voranigo is used after a biopsy or surgery to remove the tumor.
40 kg or more
Children’s Dosage
Voranigo is approved for kids aged 12 or older. However, it hasn't been studied in children younger than 12 years old.
Dosage
40 mg once per day
- Form: oral tablet
- Strengths: 10 mg and 40 mg
- Adults: The usual dose is 40 mg once a day. If you're taking a lower dose, make sure to follow your doctor's instructions.
- Children: The dose depends on the child's weight, with lighter kids taking 20 mg once a day and heavier kids taking 40 mg once a day.
Important things to remember:
- When to take: Try to take Voranigo around the same time every day.
- If you miss a dose: If it's been less than 6 hours since the dose was due, take the missed dose as soon as possible. If it's been more than 6 hours, skip the missed dose and wait for your next dose.
- Taking Voranigo with food: Voranigo can be taken with or without food.
- Crushing, splitting, or chewing Voranigo: Swallow the tablets whole with water. If you have trouble swallowing, consult your doctor or pharmacist.
- Length of use: Voranigo is meant for long-term use. You'll likely take it for an extended period unless your doctor prescribes otherwise.
- Length of time to work: Voranigo starts working immediately, but the benefits might not be noticeable to you.
Overdose
Don't take more Voranigo than your doctor recommends. If you believe you've taken too much, contact your doctor or reach out to the Poison Control Hotline: 1 (800) 222-1222.
Voranigo Interactions
Voranigo can react with several other medications. Before taking Voranigo, make sure to discuss your current medications, as well as any vitamins, herbs, or supplements you take, with your doctor and pharmacist to avoid potential interactions.
Alcohol Interaction
Avoid alcohol while taking Voranigo, as both may cause similar side effects like headache, nausea, diarrhea, and liver problems.
Alternatives
Other brain tumor treatments exist, such as chemotherapy and radiation therapy, but they might not be the right fit for your unique health situation. If you're interested in alternatives, discuss your options with your doctor.
Things to consider when taking Voranigo
• ciprofloxacin (Cipro)• cyclosporine (Neoral, others)• fluvoxamine (Luvox)• phenytoin (Dilantin, Phenytek)• rifampin (Rifadin, Rimatane)• hormonal forms of birth control, such as the combined pill, minipill, or patch
- Pregnancy: Voranigo can cause fetal harm and should generally not be taken during pregnancy. Discuss your pregnancy plans with your doctor before taking this medication.
- Fertility: Voranigo can reduce fertility in both males and females. If you want to have children in the future, talk with your doctor about your options before starting this treatment.
- Birth control: If you're female, use non-hormonal forms of birth control, such as condoms, while taking Voranigo and for three months after your last dose. Voranigo can make some forms of hormonal birth control less effective.
- Breastfeeding: Voranigo should not be taken while breastfeeding. Discuss your breastfeeding plans with your doctor before taking this medication.
- Voranigo is a brand-name pill used in the treatment of certain types of brain tumors, specifically grade 2 astrocytomas and oligodendrogliomas in adults and children aged 12 or older.
- This medication is categorized as an isocitrate dehydrogenase-1 and isocitrate dehydrogenase-2 inhibitor, a type of targeted cancer therapy.
- Since Voranigo is currently not available in a generic form, it requires a prescription and is not a controlled substance.
- Voranigo may trigger mild side effects like fatigue, headache, nausea, diarrhea, and muscle or joint pain, but more serious side effects like liver problems, seizures, and allergic reactions can also occur.
- Children's dosage of Voranigo depends on their weight, with lighter kids taking 20 mg once a day and heavier kids taking 40 mg once a day.
- It is crucial to discuss with your doctor other medical conditions, current medications, and any vitamins, herbs, or supplements you take, as they might interact with Voranigo. Additionally, if you're pregnant, breastfeeding, or plan to become pregnant, you should consult your doctor about the use of this medication.
