Dosage Information for Ingrezza: Forms, Strengths, Administration, and Additional Details
Ingrezza, a brand-name drug, has been approved by the Food and Drug Administration (FDA) to treat chorea related to Huntington's disease and tardive dyskinesia, two debilitating movement disorders. This oral medication comes in three strengths: 40 mg, 60 mg, and 80 mg.
For those starting on Ingrezza, the typical dosage is 40 mg once per day. After a week, this can be increased to 80 mg daily, if tolerated. However, an alternative maintenance dose of 60 mg once daily may be used based on the patient's response.
It's important to note that Ingrezza should be taken once per day, with or without food. Doctors may also adjust dosages for people with difficulty breaking down the drug. If you have questions about your dosage, talk to your doctor or pharmacist.
Ingrezza is designed for long-term use. However, if you miss a dose, take it as soon as you remember, but do not double up or take two doses to make up for a missed dose.
Ingrezza comes as oral capsules, and for those who have difficulty swallowing pills, there are also Ingrezza Sprinkle capsules. These can be opened and the contents sprinkled over soft food. Some pharmacies also offer labels with large print, braille, or a code you scan with a smartphone to convert text to speech.
When it comes to potential interactions, while specific interactions for Ingrezza were not detailed, similar drugs like tetrabenazine require dose adjustments for patients who are poor metabolizers of CYP2D6 or who take strong CYP2D6 inhibitors (e.g., paroxetine, fluoxetine). Since Ingrezza is also metabolized by CYP enzymes, dose adjustments might be needed if taken with such inhibitors, but explicit guidance was not found in the current data.
In the case of liver disease, while no explicit dose adjustments for liver impairment in Ingrezza were found, similar drugs (amantadine and chlordiazepoxide) require caution or dose reductions in liver dysfunction. As such, cautious use and possible dose adjustment in hepatic impairment would be prudent, pending specific medical advice.
Ingrezza is not available in a generic version at this time. If you take more than the recommended amount of Ingrezza, call your doctor right away. If you have trouble reading prescription labels, discuss this with your doctor or pharmacist.
In conclusion, Ingrezza offers a new treatment option for adults living with movement disorders. Always consult with your healthcare provider for personalised dosage advice and to discuss potential interactions with other medications.
- The Food and Drug Administration (FDA) has approved Ingrezza, a brand-name drug, for treating chorea related to Huntington's disease and tardive dyskinesia, two debilitating movement disorders.
- Ingrezza comes as oral capsules, and there are also Ingrezza Sprinkle capsules available for those who have difficulty swallowing pills.
- If you miss a dose of Ingrezza, take it as soon as you remember, but do not double up or take two doses to make up for a missed dose.
- When it comes to potential interactions, dose adjustments might be needed if taking Ingrezza with CYP2D6 inhibitors, but explicit guidance was not found in the current data. Cautious use and possible dose adjustment in hepatic impairment would be prudent, pending specific medical advice.
