Overview
Experiencing Side Effects from Ativan: Understanding Their Nature and Appropriate Responses
Lorazepam, marketed under the brand name Ativan, is a prescription medication used in two forms: oral tablets and injections. The Food and Drug Administration (FDA) has approved its use for:
- Treatment of anxiety disorders and anxiety associated with depression. Ativan is suitable for adults and teenagers aged 13 years and older for these conditions.
- Management of status epilepticus and assistance during anesthesia in adults.
Typically, Ativan is prescribed for short-term use.
Here are some key details about Ativan:
- Active ingredient: Lorazepam
- Drug class: Benzodiazepines
- Drug forms:
- Oral tablets
- Solution for either intravenous or intramuscular injection administered by a healthcare professional
Bear in mind that Ativan, like other medications, can result in side effects. Keep reading to explore common, mild, and severe side effects. For a thorough overview of Ativan, including its uses, refer to this resource.
More prevalent side effects of Ativan
Ativan can produce various side effects, some of which are more frequent than others. These side effects may be temporary, lasting a few days to weeks. If they persist longer, worsen, or become bothersome, consult your doctor or pharmacist.
Some common side effects reported in Ativan clinical trials include:
- Weakness
- Lightheadedness
- Drowsiness
- Issues with balance
- Decreased blood pressure*
Mild side effects of Ativan
Mild side effects can emerge during Ativan treatment. This list does not include all probable mild side effects of the drug. For a comprehensive overview, consult the prescribing information for Ativan tablets and injection.
Mild side effects reported with Ativan include:
- Headache
- Memory loss
- Sexual issues, such as impaired libido (sexual desire) and difficulty achieving orgasm
- Feelings of restlessness
- Weakness
- Lightheadedness
- Drowsiness
- Depression
- Confusion
- Fatigue
- Hair loss
- Reactions at the injection site, like pain, burning, or redness/discoloration, for Ativan injection users
- Digestive concerns, such as nausea, appetite changes, and constipation*
- Mild allergic reaction*†
These side effects may be transient, lasting a few days to weeks. However, if they persist longer, worsen, or become severe, consult your doctor or pharmacist.
Note: After a drug's FDA approval, they track side effects. If you develop a side effect while taking Ativan and wish to inform the FDA, visit MedWatch.
Severe side effects of Ativan
Ativan may cause severe side effects. The following list does not include all possible severe side effects of the drug. For more information, consult the prescribing information for Ativan tablets and injection.
If you experience severe side effects while taking Ativan, call your doctor immediately. If the side effects seem life-threatening or likely represent a medical emergency, call 911 or your local emergency number without delay.
Severe side effects reported with Ativan include:
- Unsteadiness
- Double vision or blurred vision
- Slurred speech or speech that is difficult to understand
- Coma
- Low body temperature
- Changes in the results of certain lab tests, such as:
- Low blood sodium (salt) level
- Low platelet count
- Low white blood cell count
- Increased liver enzymes (a potential sign of liver damage)
- Increased alkaline phosphatase levels
- Respiratory problems, symptoms of which may include:
- Slower breathing than usual
- Respiratory failure in extremely rare cases
- Jaundice and increased bilirubin levels. Symptoms may include:
- Yellow discoloration of skin and eyes
- Abdominal pain
- Thoughts of suicide or suicide attempts. Warning signs can include:
- Suicidal thoughts
- Isolation from friends and family
- Paradoxical reaction to Ativan. A paradoxical reaction is the opposite effect expected from a drug. Symptoms can include:
- Anxiety
- Agitation
- Feelings of anger or hostility
- Aggression
- Insomnia
- Sexual arousal
- Hallucinations*
- Risk of dependence and withdrawal.† (For more information, refer to the section "Ativan withdrawal symptoms" below.)
- Life-threatening side effects when Ativan is combined with opioid medications.†
- Low blood pressure.†
- Seizures.†
- Severe allergic reaction.†‡
- Risk of misuse and addiction.† (For more details, see the "Ativan misuse" section below.)
Long-term effects of Ativan
Ativan is primarily intended for short-term use. Prolonged use of Ativan beyond 4 months, as per clinical trials of the drug's tablets, hasn't been extensively studied. Extended Ativan intake may elevate the likelihood of dependency and withdrawal symptoms.
Should you have any queries related to Ativan usage duration or its possible impacts, consult your physician.
Side effects in the adolescent population
Ativan tablets have FDA approval for treating anxiety in adolescents aged 13 years and above.
Adolescents might be more susceptible than adults to experiencing unintended effects from Ativan. An unintended effect is one that is the polar opposite of what was anticipated. (More information on this side effect can be found in the "Serious side effects of Ativan" section above.)
If you're concerned about your adolescent's Ativan side effects, engage with their doctor.
Please note that Ativan tablets are not approved for use in adolescents below 12 years of age. Ativan injection, too, is not intended for use in this age group.
Ativan withdrawal symptoms
Ativan tablets and Ativan injection carry warnings about the potential for dependency and withdrawal. However, this side effect was not common in the clinical trials of Ativan's tablets or injection.
With dependency, an individual becomes reliant on the drug to function as usual. With withdrawal, symptomatic responses surface when the drug intake is abruptly halted. Long-term usage of Ativan may increase the probability of withdrawal. And suddenly stopping Ativan or reducing its dosage can lead to withdrawal symptoms.
These symptoms, ranging from mild to severe, can include:
- Odd bodily movements
- Muscle soreness and stiffness
- Anxiety or panic attacks
- Blurred vision
- Depression
- Lightheadedness
- Fatigue
- Digestive problems (like nausea, vomiting, and diarrhea)
- Headache
- Sensitivity to light
- High blood pressure or heightened heart rate
- Memory issues
- Sleeplessness
Severe withdrawal symptoms can include:
- Suicidal thoughts or behaviors
- Seizures or convulsions
- Depression
- Hallucinations
- Mania
- Psychosis
If these symptoms manifest, they typically last for a short period. In rare cases, they may persist for up to 12 months. If you encounter severe withdrawal symptoms, seek urgent medical aid.
Should you wish to cease Ativan treatment, consult your doctor. Avoid haltstatic it yourself.
Suicide prevention
If you come across someone at imminent risk of self-harm, suicide, or harming others:
- Address the problem directly: "Are you contemplating suicide?"
- Listen attentively without judgment.
- Reach out to 911 or your local emergency number, or text TALK to 741741 to communicate with a trained crisis counselor.
- Stay with the individual until professional help arrives.
- If feasible, remove any hazardous objects from the vicinity (weapons, medications, etc.).
If you or someone you know is contemplating suicide, a prevention hotline can provide assistance. Dial 988 for the 24/7 988 Suicide and Crisis Lifeline. For emergency assistance, deaf and hard-of-hearing individuals can use their preferred relay service or dial 711 then 988.
Explore additional links and local resources.
Ativan side effects in the elderly
Individuals aged 65 years or above may be more prone to drowsiness and imbalance while using Ativan. They may also be more sensitive to the paradoxical effects of Ativan. (More information on this side effect can be found in the "Serious side effects of Ativan" section above.)
If you fall under this age group and are concerned about the side effects of Ativan, speak with your doctor.
FAQs about Ativan's side effects
Ativan can potentially lead to various side effects. Below are some frequently asked questions about Ativan's side effects and their answers.
Do 1-mg and 2-mg Ativan tablets show the same side effects as other forms?
Generally, diversified strengths of Ativan tablets might trigger similar side effects. However, higher dosages of Ativan tablets may result in more pronounced adverse effects. Yet, this can vary from individual to individual.
It is important to note that not every user will experience side effects during Ativan treatment. Discuss your concerns about side effects with your doctor if you start taking Ativan.
Is weight gain one of Ativan's side effects?
No, weight gain is not typically a side effect of Ativan. It was not reported in the clinical trials of Ativan's tablets or injection.
If you have anxiety and/or depression, weight fluctuations may occur due to these conditions. Alternatively, you might experience weight loss if you develop certain side effects of Ativan treatment, such as nausea, loss of appetite, or withdrawal.
Should you be worried about weight changes during Ativan treatment, engage with your doctor.
Explore some potential side effects associated with Ativan use. To gain insight into how frequently these side effects occurred in clinical trials, refer to the prescribing information for Ativan in both tablet and injection form.
Potential fatal interactions with opioids
Ativan carries a warning regarding the risk of life-threatening effects when used in conjunction with opioid medications. This is a serious caution issued by the Food and Drug Administration (FDA). Boxed warnings serve to warn doctors and patients about potentially harmful drug side effects. Although this particular risk was not common in Ativan tablet and injection clinical trials, it is crucial to be aware of this potential danger.
Combining Ativan and opioids can lead to the following life-threatening side effects:
- intense drowsiness
- respiratory depression (slow breathing rate)
- coma
- potentially fatal consequences if immediate medical attention is not sought
Recommendations
Should you experience any of the aforementioned side effects, it is imperative to seek immediate medical assistance. Dial 911 or your local emergency number.
Before commencing Ativan treatment, inform your healthcare provider if you are currently using any opioid medications. Ativan will only be prescribed in conjunction with opioids if no alternative treatment options exist for your condition.
If your physician recommends Ativan and opioid use concurrently, they may prescribe a lower Ativan dose for a limited duration. Additionally, they may prescribe naloxone (Narcan). This medication serves as an emergency treatment for respiratory depression caused by opioid overdose. The use of Ativan and opioids can lead to side effects similar to opioid overdose, making naloxone a necessary consideration.
Nausea
Nausea has been reported as a side effect of Ativan by some individuals. This side effect was relatively uncommon in clinical trials involving Ativan tablets and injection. Typically, nausea symptoms will dissipate throughout your treatment course.
Potential solutions
To minimize the impact of nausea from Ativan tablets, consider implementing the following strategies:
- consume your Ativan dose along with some crackers or toast
- avoid lying down immediately following medication administration
- try sipping water or consuming small amounts of crushed ice
If your nausea persists or worsens during Ativan treatment, communicate your concerns with your healthcare provider. They may offer alternative coping mechanisms to address this side effect.
Should you experience nausea from an Ativan injection, inform your healthcare provider or another medical professional. They can provide assistance to alleviate this unwanted symptom.
Hallucinations
In rare cases, individuals have reported hallucinations during Ativan tablet and injection clinical trials. Hallucinations refer to experiencing perceptions that are not grounded in reality.
Potential solutions
If you encounter hallucinations while using Ativan, consult with your healthcare provider. They may recommend a different medication to address your condition.
Low blood pressure
Ativan can potentially result in severe low blood pressure as a side effect, although this side effect was relatively uncommon in clinical trials involving Ativan tablets and injection. Symptoms of low blood pressure may include:
- dizziness
- instability
- lightheadedness
- increased likelihood of falling
- fainting
Potential solutions
Should you experience any of the aforementioned symptoms during Ativan treatment, notify your healthcare provider. Inform them if you take any medications to manage your blood pressure. They may adjust their monitoring of your blood pressure throughout your treatment course.
Seizures
The use of Ativan can increase the risk of seizures in individuals with a history of seizure disorders. This side effect was relatively rare in Ativan tablet and injection clinical trials. Symptoms may include:
- involuntary, jerky movements in your limbs
- muscle stiffness
- loss of consciousness
- staring spells, potentially indicative of an absence seizure (brief periods of unconsciousness devoid of motor activity)
Potential solutions
If you believe that you have experienced a seizure while using Ativan, contact 911 or your local emergency number immediately. Inform your healthcare provider of this occurrence, as they may recommend an alternative treatment strategy for your condition.
Allergic reactions
Allergic reactions are possible after Ativan consumption. This side effect was reported in clinical trials involving Ativan tablets. It remains unclear whether an allergic reaction occurred during Ativan injection clinical trials. Symptoms may be mild or severe, including:
- skin rash
- itching
- flushing
- rapid heartbeat
- swelling under the skin, typically affecting the eyelids, lips, hands, or feet
- swelling of the mouth, tongue, or throat, potentially impairing your ability to breathe
Potential solutions
For mild allergic reaction symptoms, contact your healthcare provider. They may suggest potential methods to alleviate these symptoms and evaluate whether further Ativan use is appropriate. In the event of more severe symptoms and suspected medical emergency, immediately contact 911 or your local emergency number.
- Potential for Misuse and Addiction. For additional info, check out the "Ativan and Misuse" segment below.
- Chance of Dependence and Withdrawal. To delve deeper, explore the "Ativan Withdrawal Symptoms" section above.
- Possibility of Severe Side Effects when Combined with Opioid Drugs. For detailed info, refer to the "Side Effect Specifics" section above.
Additional Precautions
It's crucial to confer with your doctor about your medical history prior to consuming Ativan. This drug might not be the suitable option for you if you have certain health issues or factors that may impact your wellness. These are referred to as drug-condition or drug-factor interactions. The conditions and factors to consider include:
Respiratory Issues. Ativan can slow down your respiratory rate. If you have conditions like sleep apnea, chronic obstructive pulmonary disease, or other respiratory problems, make sure to inform your doctor. They will provide guidance regarding the use of Ativan in your specific case.
Mental Health Concerns. Ativan is prescribed to alleviate anxiety related to depression. Nonetheless, it can worsen depression* symptoms. If you have depression, share this information with your doctor. They might recommend treatment for your depression before prescribing Ativan.
Kidney or Liver Issues. Your kidneys and liver help eliminate medications from your body. If you have kidney or liver problems, inform your doctor. They might prescribe a reduced dosage of Ativan.†
Acute Narrow-Angle Glaucoma. Ativan can exacerbate glaucoma by raising the pressure inside the eye. Doctors usually don't prescribe Ativan if you have acute narrow-angle glaucoma. Make sure to disclose this condition to your doctor.
Allergic Reactions. If you've had an allergic reaction‡ to Ativan or any of its components, your doctor may not prescribe the drug. Consult your doctor about alternative medications that might be suitable for you.
Current Usage of Opioid Medication. If you're currently on opioids, make sure to inform your doctor. Combining opioid drugs with Ativan can lead to life-threatening side effects.
Alcohol and Ativan
Avoid consuming alcohol while undergoing Ativan treatment. Alcohol may enhance the risk of serious side effects of the drug, such as:
- breathing difficulties, including respiratory depression (slow breathing)
- memory problems
- extreme drowsiness
- coma
Ativan can also reduce your alcohol tolerance. This means you may feel the effects of alcohol more than usual after a drink.
If you have questions regarding alcohol consumption while on Ativan, reach out to your doctor.
Ativan and Pregnancy/Breastfeeding
It's not safe to take Ativan during pregnancy. Exposure during the third trimester may harm the fetus. Newborns who were exposed to Ativan during pregnancy may experience withdrawal symptoms after birth. (For more details, see the "Ativan Withdrawal Symptoms" section above.)
Before starting treatment with Ativan, inform your doctor if you're pregnant or planning to become pregnant. They will recommend the most suitable treatment option for you.
If you're breastfeeding, you should not take Ativan. Doing so may cause side effects in your child because the drug is known to pass into breast milk. Discuss safe feeding options with your doctor.
Ativan and Misuse
Ativan carries a warning about the risk of misuse. This is a serious notice from the Food and Drug Administration (FDA). Boxed warnings serve to alert doctors and patients about drug effects that may be dangerous.
Misuse of Ativan involves using the drug in a manner or for a purpose not prescribed by your doctor. Misuse of Ativan can result in addiction or overdose. In extremely rare cases, it can be life-threatening.
Indicators of misuse may include:
- nausea and vomiting
- sweating
- muscle weakness
- body aches
- nightmares
- depression
- anxiety
The risk of misuse is higher for individuals with a history of substance abuse. It's also higher for people who take high doses of Ativan or use it for extended periods.
Given the above risks, it's essential to take Ativan precisely as directed by your doctor. Combining Ativan with other medications, alcohol, or illegal drugs may increase the risk of harmful outcomes. Share all the medications you take and if you've ever had issues related to substance abuse with your doctor.
When to Contact Your Doctor
Treatment with Ativan can lead to mild and severe side effects. While most side effects are uncommon, if they occur, they usually tend to be mild.
However, Ativan can cause serious side effects in rare cases. Inform your doctor if you experience side effects that are severe or bothersome. For more information, refer to the "Side Effect Specifics" section above.
If you'd like to learn more about Ativan, consult with your doctor or pharmacist. They can assist you in addressing any concerns you have regarding the drug's side effects.
Besides consulting with your doctor, you can conduct your own research. These articles might provide helpful information:
- More details about Ativan. For more insights on various aspects of Ativan, consult this article.
- Comparing Drugs. Get a comprehensive understanding of how Ativan stacks up against other medications like Xanax, Klonopin, Valium, and Ambien.
- Dosage Information. To learn about Ativan's dosage guidelines, check out this article.
- Drug Interactions. Dive deeper into Ativan's interactions with other substances by reading this article.
- Understanding Your Situation. Here are some resources to help you gain a better understanding of your condition:
- For in-depth information on anxiety, visit our anxiety center.
- To learn more about seizures, check out our epilepsy and seizure hub.
Disclaimer:Medical News Today has made every effort to ensure that all information is accurate, comprehensive, and up-to-date. However, this article shouldn't be used as a replacement for the advice of a licensed healthcare professional. Always consult with your doctor or another healthcare expert before starting any medication. The medication information provided here is subject to change and is not intended to cover all possible uses, dosages, precautions, warnings, drug interactions, allergic reactions, or side effects. The absence of warnings or other information for a specific drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
In light of the information provided about Ativan, here are two sentences that incorporate the given words:
- Patients with epilepsy should be cautious when using Ativan, as it may exacerbate symptoms in some individuals and can interact with other seizure medications.
- managing mental health conditions like anxiety and depression often involves the consideration of pharmaceutical interventions, such as Ativan, which can help alleviate symptoms but may require the monitoring of potential side effects, like drowsiness and decreased blood pressure.
