Length of Immune Protection Provided by the "Sputnik V" Vaccination Revealed
In a recent statement, Yerlan Kiiasov, Vice Minister of Health and Chief State Sanitary Doctor of Kazakhstan, urged the public to trust only official information regarding COVID-19 vaccines. He emphasised that the vaccine, particularly Russia's Sputnik V, protects against moderate and severe COVID-19.
Current evidence shows that Sputnik V is about 91.6% effective against the original SARS-CoV-2 strain, according to Phase III trial data published in The Lancet as of mid-2025. This effectiveness is comparable to many leading vaccines, indicating strong protection.
Regarding the duration of immunity, while direct data specifically on Sputnik V's long-term immunity are limited in the latest sources, the broader COVID-19 vaccine research indicates that antibody levels and neutralizing capacity generally wane over time across vaccine types. Boosters have been shown to significantly restore and sustain neutralizing antibody levels against variants, suggesting a similar booster approach might be needed for Sputnik V as well.
Concerning efficacy against SARS-CoV-2 variants of concern such as the British (Alpha) and South African (Beta) strains, no detailed data specific to Sputnik V’s neutralizing antibody performance against these variants appear in the current search results. However, it is known that many vaccines show some reduction in neutralizing capacity against variants like Beta and others. Given Sputnik V's adenovirus vector platform similar to some other vaccines, it is plausible its neutralization against variants is also somewhat reduced, but comprehensive variant-specific efficacy data would need to be confirmed by ongoing or future studies.
The Sputnik V vaccine has been proven effective against the British and South African strains, as well as moderate and severe COVID-19, according to the facts. The Ministry of Health has promised to conduct an investigation for any adverse effects after the COVID-19 vaccine. The specific adverse effects that the Ministry of Health will investigate are not specified.
Yerlan Kiiasov believes that the vaccination campaign is a key measure to return to normal society. The vaccination campaign is still ongoing, and the COVID-19 vaccination is free of charge, as it is funded by the state budget. It is important to note that vaccination against COVID-19 is voluntary in Kazakhstan.
The Sputnik V vaccine is reported by Almaty.tv, and the vaccination drive is ongoing across the country. While fake news about the harm of COVID-19 vaccines is circulating on social media, it is crucial to rely on official information to make informed decisions about vaccination.
Given the effectiveness of Sputnik V against the original SARS-CoV-2 strain, as well as moderate and severe COVID-19, it's essential to trust only official information about the vaccine's medical-conditions and health-and-wellness benefits. Furthermore, as the vaccine's long-term immunity data are limited, ongoing studies may provide insights into the need for booster doses to maintain protective levels against variants.
