Voranigo: Details on Cost, Adverse Effects, Applications, Dosage, and Additional Information
Hollerin' About Voranigo:
Voranigo is a tasty little pill, designed to help out certain types of brain tumors, known as astrocytomas and oligodendrogliomas. Now, ain't that a mouthful? But don't worry, we'll break it down for ya.
This stylish oral tablet packs a punch thanks to its active ingredient: vorasidenib. Yeah, we know, ain't as catchy as "Voranigo," but it does the trick.
Our friends at the Food and Drug Administration (FDA) have given the green light to use Voranigo in adults and youngsters 12 years and older, when it comes to treating these particular brain tumors in specific situations. (See the "Voranigo uses" section for all the juicy details.)
Now, here's the lowdown on Voranigo:
- It's a type of targeted cancer therapy, specifically an isocitrate dehydrogenase-1 and isocitrate dehydrogenase-2 inhibitor. Confused? Don't fret, that just means it goes after certain proteins in your cancer cells that help 'em grow out of control.
- You won't find a generic version of Voranigo floating around. It's only available in brand-name form, for now.
- Like all medications, the price can vary depending on factors such as your insurance, location, and pharmacy. Though, there's financial assistance available through the ServierONE program for those in need (see "Voranigo cost and coupons" section).
Side effects of Voranigo can range from mild to serious, but most of 'em should fade away with time. As with any med, if they don't or they become bothersome, reach out to your doctor or pharmacist.
Now, let's dive deeper into Voranigo's cool uses, side effects, and all the deets in between. Time to get schooled!
Voranigo: The Brain Tumor Slayer
Voranigo has earned its stripes by being approved by the FDA to squash grade 2 astrocytomas and oligodendrogliomas in adults and kids aged 12 and up. These suckers are part of a family of brain tumors called gliomas. Astrocytomas call brain cells called astrocytes home, while oligodendrogliomas settle in oligodendrocytes. Both types play an essential role in your brain, but when they go astray, they can grow into tumors.
less than 40 kg (about 88 pounds [lb])
These brain tumors are graded from 1 to 4 depending on how fast they're expected to grow and spread. Grade 2 astrocytomas and oligodendrogliomas are slow-growing, low-grade tumors. Even though they're not expected to grow too fast, they can creep into nearby brain tissue.
Voranigo defends your brain by targeting these tumors with a specific genetic mutation (an abnormal change in a gene). It targets IDH1 or IDH2 mutations, which, if you recall, are enzymes that help cells produce energy. These mutations make the enzymes wonky, and they produce a molecule that fuels tumor growth. Voranigo blocks these bad boys from doing their dirty work, keeping the tumors at bay.
20 mg once per day
Voranigo Side Effects:
Like any medication, Voranigo can cause some unwanted effects. Some might be mild, while others could be a bit more serious. Don't freak out if you experience some of these sidies—they're a normal part of the ride. But if they become severe or won't go away, chat with your doctor or pharmacist.
Mild Side Effects:
40 kg or more
- Fatigue
- Headache
- Nausea
- Diarrhea
- Constipation
- Reduced appetite
- Muscle or joint pain
- COVID-19
- Lowered white blood cell count
- Increased liver enzymes
40 mg once per day
Voranigo Uses:
Voranigo for certain brain tumors:
Voranigo is a righteous solution for treating certain brain tumors, specifically grade 2 astrocytomas and oligodendrogliomas. You'll find the prescription for It when these tumors show a specific genetic mutation, an IDH1 or IDH2 mutation. Before prescribing Voranigo, your doctor will likely test for this mutation using a biopsy or surgery to remove part of the tumor.
Enrichment Data:
As of May 2025, you won't find a generic version of Voranigo cruising the shelves. It was only recently approved by the FDA in August 2024 for treating grade 2 astrocytomas or oligodendrogliomas with susceptible IDH1 or IDH2 mutations in patients aged 12 years and older[1][2]. Since it's new-kid-on-the-block status, a generic version isn't on the market yet.
Generally, the availability of a generic version relies on factors such as patent protections, exclusivity granted by the FDA, and when generic manufacturers file for approval. Given Voranigo's recent approval, it likely has some protections in place that could last several years before generics become available (usually around 5-7 years post-FDA approval).
This means a generic Voranigo might take a few more years to hit the market. At this point, there's no announced date for the generic version's arrival.[1][3] Stick to obtaining Voranigo from legitimate pharmacies to stay clear of counterfeit products.[1]
• ciprofloxacin (Cipro)• cyclosporine (Neoral, others)• fluvoxamine (Luvox)• phenytoin (Dilantin, Phenytek)• rifampin (Rifadin, Rimatane)• hormonal forms of birth control, such as the combined pill, minipill, or patch
[1] "Drug-Specific Information: Voranigo" (Medicare.gov)
[2] "U.S. FDA Approves Voranigo (vorasidenib) for Adult Patients and Children 12 Years and Older with IDH1- or IDH2-Mutant Astrocytoma or Oligodendroglioma" (Servier)
[3] "FDA Approved Drugs List" (FDA.gov)
- Voranigo, designed to help certain types of brain tumors, includes the treatment of other brain disorders like cancer.
- This medication is a type of targeted science, working as an isocitrate dehydrogenase-1 and isocitrate dehydrogenase-2 inhibitor, which is a crucial aspect of neurological health-and-wellness.
- The drug is commonly used to manage medical-conditions like cancer, specifically grade 2 astrocytomas and oligodendrogliomas, in both adults and children aged 12 and older.
- Other brain disorders, such as mental-health conditions, might benefit from advancements in oncology research, particularly in relation to targeted therapies like Voranigo.
- It's essential to understand the side effects, costs, and interactions of Voranigo and other drugs when considering treatment for various brain disorders, as part of ongoing health-and-wellness management.
